KETOCONAZOLE TABLET

KETOCONAZOLE TABLET

Indications:

It can be used for systemic fungal infections such as systemic candidiasis, paraccidioidomycosis, histoplasmosis, coccidioidomycosis and blastomycosis.

Contra-indications:

Contraindicated if known to be allergic to ketoconazole or any component of this product.
Contraindicated in patients with acute and chronic liver disease.
Prohibited for pregnant women.

Adverse Effects:

Gastrointestinal tract, hepatobiliary system
Common: nausea, vomiting, abdominal pain.
Rare: Diarrhea, dyspepsia, reversible liver enzyme elevation.

Drug Interactions:

Drugs that affect ketoconazole metabolism
Enzyme-induced drugs, such as rifampicin, rifampudding, carbamazepine, isoniazid, and phenytoin, significantly reduce the bioavailability and efficacy of ketoconazole.

Precautions & Warning:

Cases of severe hepatotoxicity, including fatal or requiring liver transplantation, are extremely rare, and a small number of patients have no significant risk factors for liver disease. A few cases appeared within one month of starting treatment, and a few cases appeared within one week of starting treatment.

Use in Pregnancy and Nursing Mothers:

Prohibited for pregnant and lactating women.

Storage instructions:

Store below 25℃. Protect from moisture. Keep out of reach of children.